Potential Health Effects of Chemical Constituents
The
following list includes chemicals found in common automotive, custodial, and
maintenance products. Each description includes the health effects associated
with exposure to the chemical. These include acute effects (those causing
severe symptoms that develop rapidly and may reach a crisis) as well as chronic health
effects (those causing long-term damage often through repeated or prolonged
exposure).
For more information on the health effects of a specific chemical, visit resources.
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A
ACETONE
Acute health effects: Contact can irritate skin. Exposure can irritate
eyes, nose, and throat. Exposure in high concentration can cause dizziness,
lightheadedness, and unconsciousness.
Chronic health effects: Repeated skin exposure can cause dryness and
cracking. Acetone has not been specifically evaluated, however, other solvents
and petroleum-based chemicals have been shown to cause brain or nerve damage,
including memory loss, personality changes, fatigue, sleep disturbances, and
reduced coordination, with repeated exposure.
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AMMONIA
Acute health effects: Can cause headache, loss of sense of smell, nausea,
and vomiting. Can irritate skin and eyes, leading to permanent damage. Can
irritate nose, mouth, and throat, causing coughing and wheezing. Can irritate
lungs, causing coughing and/or shortness of breath; higher exposures can cause
a build-up of fluid in the lungs.
Chronic health effects: Repeated exposure can cause chronic irritation
of the eyes, nose, throat, and lungs. Repeated exposures may cause bronchitis,
with cough, phlegm, and/or shortness of breath.
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ARSENIC
Acute health effects: May irritate skin, eyes, nose, and throat; high
exposure can cause poor appetite, nausea, vomiting, and muscle cramps.
Chronic health effects: A carcinogen, shown to cause skin and lung
cancer. High or repeated exposure can damage the liver and the nerves, with “pins
and needles,” burning, numbness, and weakness of arms and legs. Repeated
skin contact can cause thickening and color changes including patchy areas
of darkening and loss of pigment.
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B
BENZENE
Acute health effects: Can cause symptoms of dizziness, lightheadedness,
headache, and vomiting. Can irritate nose, throat, eyes, and skin. Convulsions
and coma, or sudden death from irregular heartbeat, may follow high-level exposure.
Chronic health effects: A carcinogen shown to cause leukemia. Repeated
exposure can cause aplastic anemia, which may lead to death. Exposure can cause
drying and scaling of the skin.
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2-BUTOXYETHANOL
Acute health effects: Can irritate eyes, nose, mouth, and throat. Exposures
at high levels can cause dizziness, lightheadedness, and unconsciousness.
Chronic health effects: May damage liver and kidneys. Long-term exposure
may break down red blood cells, causing anemia. May be a teratogen, causing
damage to a developing fetus.
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n-BUTYL ALCOHOL
Acute health effects: Can irritate skin, causing a burning sensation
or rash on contact. Can irritate and burn eyes, leading to tearing and damage.
Inhalation can cause coughing, wheezing, and shortness of breath, headache,
nausea, vomiting, and dizziness; higher levels can cause unconsciousness and
irregular heartbeat.
Chronic health effects: Repeated contact may cause drying and cracking
of skin. Exposure can damage liver, heart, kidneys, hearing, and sense of balance.
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C
CADMIUM
Acute health effects: Can cause a flu-like illness with chills, headache,
aching, and/or fever. Exposure at high levels may cause nausea, salivation,
vomiting, abdominal cramps and diarrhea. Inhalation can irritate lungs, causing
coughing and/or shortness of breath; higher levels can cause a build-up of
fluid in the lungs.
Chronic health effects: A probable carcinogen; there is evidence for
prostate and kidney cancer in humans. A probable teratogen that may also affect
both male and female reproductive organs. Can irritate lungs; repeated exposure
may cause bronchitis with cough, phlegm, and/or shortness of breath. Repeated
low-level exposures can cause permanent kidney damage. Long-term exposure can
damage the liver and cause anemia, loss of sense of smell, and fatigue.
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CARBAMATES
Acute health effects: Can cause headache, dizziness, weakness, shaking,
nausea, stomach cramps, diarrhea, and sweating.
Chronic health effects: Can cause loss of appetite, weight loss, and
general feeling of sickness.
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CHLORINATED HYDROCARBONS (a.k.a. ORGANOCHLORINES)
Acute health effects: May cause headache, dizziness, weakness, shaking,
nausea, excitability, disorientation, and rashes.
Chronic health effects: May disrupt the function of the nervous system,
especially the brain. May accumulate in fatty tissues. May cause nervousness,
weakness, and shaking.
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CHLORINE
Acute health effects: Can irritate the eyes, nose, and throat, causing
tearing, coughing, and bloody nose. Inhalation can irritate the lungs, causing
coughing, shortness of breath, and chest pain; exposures at higher levels can
cause a build-up of fluid in the lungs. Direct contact can severely irritate
and burn the eyes and skin, causing permanent damage.
Chronic health effects: Repeated exposures may cause bronchitis with
cough, phlegm, and/or shortness of breath, and may permanently damage the lungs.
Long-term exposure can damage the teeth and cause a skin rash.
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CHROMIUM
Acute health effects: Inhalation can cause “metal fume fever” (a
flu-like illness with metallic taste in the mouth) as well as headache, fever,
chills, aches, chest tightness, and cough.
Chronic health effects: May cause skin allergy, leading to itching
and skin rash with very low exposure.
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COPPER
Acute health effects: Inhalation can irritate eyes, nose, and throat,
causing coughing, wheezing, nosebleeds, and/or “metal fume fever” (a
flu-like illness with symptoms of metallic taste), as well as fever, chills,
aches, chest tightness, and cough.
Chronic health effects: May decrease fertility in males and females.
Repeated exposure may damage the liver. Repeated exposure can cause chronic
irritation of nasal membranes, including ulcers in the nose. Repeated exposure
may cause thickening of skin and add a greenish color to the skin, teeth, and
hair.
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CRESOLS
Acute health effects: At high levels, exposure can cause collapse and
death within minutes. Exposure can irritate the nose and throat and severely
burn the skin and eyes, causing permanent damage.
Chronic health effects: Repeated exposure may damage the liver and
kidneys. Long-term exposure can lead to chronic poisoning, with trouble swallowing,
loss of appetite, vomiting, diarrhea, headache, and dizziness.
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D
2,4-D
Acute health effects: Can cause severe irritation of the skin and eyes.
Inhalation can irritate nose, throat, and lungs, causing coughing and/or shortness
of breath; at higher levels, exposures can cause a build-up of fluid in the
lungs. High-level or repeated exposures can cause headache, fatigue, muscle
weakness and twitching, and poor coordination in arms and legs.
Chronic health effects: Non-Hodgkin’s lymphoma has been observed
in farmers occupationally exposed to 2,4-D. Exposure may cause reproductive
damage and damage to liver and kidneys.
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DIMETHYL ETHER
Acute health effects: Inhallation of vapor can cause eye, nose, and
throat irritation; high-level exposure can cause headache, dizziness, and lightheadedness.
Skin contact with liquid form can cause severe frostbite.
Chronic health effects: Have not been established.
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DIOXIN (2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN or
TCDD)
Acute health effects: None identified.
Chronic health effects: Has caused cancer in chemical workers exposed
to high levels. Studies show that high levels of dioxin exposure can lead to
reproductive and developmental problems, increased heart disease, and increased
diabetes. The effects of dioxin on humans were observed only in populations
that were highly exposed, so the effects of long-term, low-level exposure normally
experienced by the general population are not known.
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DIQUAT DIBROMIDE
Acute health effects: May be fatal to humans if swallowed, inhaled,
or absorbed through the skin. Concentrated solutions may cause severe irritation
of the mouth, throat, esophagus, and stomach, followed by nausea, vomiting,
diarrhea, severe drying out of bodily tissues, gastrointestinal discomfort,
chest pain, diarrhea, kidney failure, and toxic liver damage. Very large doses
of the herbicide can result in convulsions and tremors. Small amounts can cause
skin irritation and sores, as well as delayed healing of cuts and wounds. Causes
eye irritation and can cause serious burns and sometimes scarring of the cornea
several days after exposure, although initial exposure caused only moderate
reactions.
Chronic health effects: Cataract formation is the most significant
effect of chronic exposure currently recognized. Effects of repeated or prolonged
skin contact range from inflammation of the skin to skin damage and/or systemic
poisoning, with injury to internal organs, primarily the liver and kidneys.
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E
ETHANOLAMINE (a.k.a. MONOETHANOLAMINE)
Acute health effects: Can cause severe eye irritation and burns, leading
to permanent damage. Contact can irritate and burn skin. Inhalation can irritate
the nose and throat and cause coughing and wheezing.
Chronic health effects: May cause liver and kidney damage. May damage
developing fetus. Repeated contact can cause redness and itching of skin.
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ETHYL ACETATE
Acute health effects: Can irritate skin, eyes, nose, and throat. High-level
exposure can cause dizziness, lightheadedness, and unconsciousness.
Chronic health effects: Has not been adequately evaluated to determine
whether brain or other nerve damage could occur with repeated exposure, but
many solvents and other petroleum-based chemicals have been shown to cause
such damage. May decrease fertility in males. Repeated contact can cause drying
and cracking of the skin.
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ETHYLENE GLYCOL
Acute health effects: Exposure can cause a “drunk” feeling,
nausea, vomiting, and headache. Can irritate eyes, nose, and throat.
Chronic health effects: May damage developing fetus. Repeated or high-level
exposure may cause kidney and brain damage.
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F
FORMALDEHYDE
Acute health effects: Contact can severely irritate and burn skin and
eyes, with possible eye damage. Burns may not appear until hours after contact.
Can irritate the lungs, causing coughing and/or shortness of breath; higher-level
exposures can cause a build-up of fluid in the lungs.
Chronic health effects: A probable carcinogen in humans. Eye contact
can cause damage, with possible loss of vision. Can irritate the lungs; repeated
exposure may cause bronchitis, with cough, phlegm, and/or shortness of breath.
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G
GLYPHOSATE
Acute health effects: Contact can irritate skin and eyes. Inhalation
can irritate nose and throat. Exposure can cause nausea, vomiting, diarrhea,
low blood pressure, and convulsions.
Chronic health effects: May damage liver and kidneys. High-level exposure
can cause irregular heartbeat and death.
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H
n-HEPTANE
Acute health effects: Exposure can cause headache, lightheadedness,
dizziness, and unconsciousness. Can irritate eyes, nose, and throat. Loss of
appetite and/or nausea may occur.
Chronic health effects: Repeated exposure may cause skin irritation
and dryness; may affect nervous system; has not been adequately evaluated to
determine whether brain damage could occur with repeated exposure but many
petroleum solvents have been shown to cause such damage.
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n-HEXANE
Acute health effects: Can irritate eyes, nose, mouth, and throat, causing
cough and/or difficulty breathing. Exposure can cause lightheadedness, giddiness,
headaches, and nausea; higher-level exposures can lead to unconsciousness and
death.
Chronic health effects: High-level or repeated exposure can damage
the nervous system, causing numbness, tingling, and/or muscle weakness in the
hands, feet, arms, and legs. Repeated skin contact can cause irritation, dryness,
and cracking, and can lead to a rash.
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HYDROCHLORIC ACID
Acute health effects: Corrosive to the eyes, skin, and mucous membranes.
Short-term inhalation may cause coughing, hoarseness, inflammation and ulceration
of the respiratory tract, chest pain, and pulmonary edema. Skin contact may
produce severe burns, ulceration, and scarring.
Chronic health effects: Long-term occupational exposure to hydrochloric
acid has been reported to cause gastritis, chronic bronchitis, dermatitis,
and photosensitization in workers. Prolonged exposure to low concentrations
may also cause discoloration and erosion of the teeth.
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L
LEAD
Acute health effects: Lead dust or fumes can irritate eyes on contact.
Inhalation of lead dust can irritate nose and throat. Exposure can cause poor
appetite, weight loss, upset stomach, nausea, and muscle cramps.
Chronic health effects: May cause kidney and brain damage and damage
to blood cells causing anemia. Probable teratogen that can damage a developing
fetus. May decrease fertility in males and females. Repeated exposure causes
tiredness, trouble sleeping, stomach problems, constipation, headaches, and
moodiness; higher levels may cause trouble concentrating and remembering things,
and aching and weakness in arms and legs. Exposure increases the risk of high
blood pressure. Accumulates in the body with repeated exposure.
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LIQUEFIED PETROLEUM GAS (propane, isobutane,
and n-butane)
Acute health effects: Exposure to very high concentrations can cause
dizziness, lightheadedness, and unconsciousness; extremely high concentrations
can cause death by suffocation from lack of oxygen. Vapor can irritate and
burn eyes. Inhalation can irritate nose and throat, causing coughing and wheezing.
Skin contact can cause frostbite.
Chronic health effects: Have not been tested.
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M
MERCURY
Acute health effects: Can irritate skin and eyes. Exposure to high
levels of vapor can irritate lungs, causing coughing, chest pain, and shortness
of breath.
Chronic health effects: Exposure may cause kidney damage. May cause
an increase in spontaneous abortions in exposed women. Repeated low-level exposures
or very high-level single exposure can cause mercury poisoning, with symptoms
including tremors, trouble remembering and concentrating, gum problems, increased
salivation, loss of appetite and weight, changes in mood and personality, hallucinations,
and psychosis. Repeated exposure may cause clouding of the eyes and a gray
skin color.
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METHYL BROMIDE
Acute health effects: Can produce central nervous system and respiratory
system failure, as well as specific and severe effects on the lungs, eyes,
and skin. Common initial symptoms include weakness, despondency, headache,
visual disturbances, nausea, and vomiting. Exposure to high concentrations
has resulted in a number of human deaths.
Chronic health effects: Central nervous system symptoms, including
numbness, defective muscular coordination, tremor, muscle spasms, lack of balance,
extreme agitation, coma, and convulsions. Exposure of pregnant women may result
in fetal defects. Depending on the dose, gross permanent disabilities or death
may result.
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METHYL ETHYL KETONE (MEK)
Acute health effects: Can irritate skin and burn the eyes, leading
to permanent damage. Inhalation can irritate eyes, nose, mouth, and throat,
causing coughing and wheezing. Exposure can cause dizziness, lightheadedness,
headache, nausea, blurred vision, and may cause unconsciousness.
Chronic health effects: Repeated exposure can damage the central nervous
system and brain, causing reduced memory and concentration, personality changes,
fatigue, sleep disturbances, reduced coordination, and/or effects on nerves
supplying internal organs and the arms and legs. Repeated exposure can cause
drying and cracking of the skin.
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METHYLENE CHLORIDE (a.k.a. dichloromethane)
Acute health effects: Liquid or vapor can irritate and burn the eyes,
skin, nose, and throat. Inhalation can irritate the lungs, causing coughing
and/or shortness of breath; higher exposures can cause a build-up of fluid
in the lungs. High-level exposure can cause headache, nausea, fatigue, dizziness,
drowsiness, and unconsciousness.
Chronic health effects: May be a carcinogen in humans. May cause liver
damage. Repeated exposures may cause bronchitis, with cough, phlegm, and/or
shortness of breath. Long-term exposure may damage the brain, causing memory
loss, poor coordination, and reduced thinking ability.
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MINERAL SPIRITS
Acute health effects: Contact and inhalation can cause eye, nose, and
throat irritation, dizziness, and dermatitis. Ingestion can induce central
nervous system depression.
Chronic health effects: Irritates skin, eyes, and respiratory tract.
Damage to lungs may result if mineral spirits are swallowed and then vomited.
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N
NAPHTHALENE
Acute health effects: Exposure can irritate skin, eyes, nose, and throat.
Very high levels can cause headache, fatigue, confusion, nausea, and vomiting.
Chronic health effects: May damage the kidneys and liver. May damage
the red blood cells, causing anemia. Repeated exposure can cause clouding of
the eye lens (cataracts), damaging vision. May cause a skin allergy, with itching
and rash at very low subsequent exposures.
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NITROBENZENE
Acute health effects: Contact can irritate the skin and eyes. High
levels can interfere with the ability of the blood to carry oxygen, causing
headache, dizziness, lightheadedness, loss of balance, weakness, and a blue
color to the skin and lips. Higher levels can cause difficulty breathing, collapse,
and even death.
Chronic health effects: Limited evidence of cancer of the liver; repeated
exposure may cause liver damage. Exposure may affect vision. May affect blood
cells, causing anemia.
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NITROGEN
Acute health effects: Not yet established.
Chronic health effects: Irritation of nose and throat. Increased susceptibility
to respiratory infections.
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O
ORGANOPHOSPHATES
Acute health effects: Can cause headache, dizziness, weakness, shaking,
nausea, stomach cramps, diarrhea, and sweating.
Chronic health effects: Can cause loss of appetite, weakness, weight
loss, and general feeling of sickness.
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P
PARAQUAT
Acute health effects: Highly toxic by all routes of exposure; many
cases of illness and death have been reported. Direct contact with paraquat
solutions or aerosol mists may cause skin burns, dermatitis, and damage to
fingernails. If splashed in the eye, can irritate, burn, and cause corneal
damage and scarring of the eyes. If swallowed, burning of the mouth and throat
occurs, followed by gastrointestinal tract irritation with abdominal pain,
loss of appetite, nausea, vomiting, and diarrhea. Other symptoms include thirst,
shortness of breath, and rapid heart rate.
Chronic health effects: Has been shown to be mutagenic in humans.
Can damage the lungs, heart, liver, kidneys, cornea of the eyes, adrenal glands,
skin, fingernails, and digestive system. Inhalation can cause nasal mucous
irritation and bleeding of the gastrointestinal tract.
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PERCHLOROETHYLENE (a.k.a. TETRACHLOROETHYLENE
ETHYLENE TETRACHLORIDE or PERC)
Acute health effects: Contact can cause skin irritation and burns.
Can irritate eyes, nose, mouth, and throat. Inhalation can irritate lungs,
causing coughing and/or shortness of breath; higher exposures can cause a build-up
of fluid in the lungs. High-level exposure can cause headache, dizziness, lightheadedness,
nausea, vomiting, and unconsciousness.
Chronic health effects: May be a human carcinogen. May damage the
developing fetus. May damage the liver and kidneys and affect the nervous system.
Long-term exposure can cause drying and cracking of the skin.
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PHENOL
Acute health effects: Inhalation can irritate the mouth, nose, throat,
and lungs, causing coughing and/or shortness of breath. Contact can cause severe
irritation and burns, with possible permanent damage to eyes and skin. High-level
exposure can cause headache, dizziness, fatigue, fainting, weakness, nausea,
vomiting, and lack of appetite; may cause collapse and death.
Chronic health effects: May be a carcinogen and mutagen. High-level
or repeated exposure may damage liver, kidneys, and heart. Effects may include
reduced memory or concentration, personality changes, fatigue, sleep disturbances,
and reduced coordination.
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PHOSPHORIC ACID
Acute health effects: Contact can severely irritate and burn the skin
and eyes, leading to permanent damage. Inhalation can irritate nose, throat,
and lungs, causing coughing and sneezing.
Chronic health effects: Repeated exposure can cause bronchitis, with
cough, phlegm, and/or shortness of breath. Long-term exposure can cause drying
and cracking of the skin.
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POTASSIUM HYDROXIDE
Acute health effects: Contact can cause severe skin and eye irritation
and burns that may lead to permanent eye damage. Exposure can irritate nose
and throat, causing sneezing, coughing, and sores in the nose.
Chronic health effects: Repeated exposure may cause holes in the nasal
septum.
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PYRETHRINS and PYRETHROIDS
Acute health effects: Inhalation may cause asthmatic breathing, sneezing,
nasal stuffiness, headache, nausea, loss of coordination, tremors, convulsions,
facial flushing and swelling, and burning and itching sensations. Symptoms
may also include loss of coordination, tremors, convulsions, paralysis, respiratory
failure, and death.
Chronic health effects: Pyrethrins and pyrethroids are of low chronic
toxicity to humans, and the most common problems have resulted from allergies.
Many of the natural and synthetic compounds can produce skin irritation, itching,
and/or pricking and local burning sensations. At high doses, pyrethrum can
be damaging to the central nervous system and the immune system.
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S
SODIUM HYDROXIDE
Acute health effects: Can cause severe irritation and burns of the
eyes, with possible permanent damage. Contact can cause severe skin irritation
and burns. Inhalation can irritate the mouth, nose, throat, and lungs, causing
coughing and/or shortness of breath; higher-level exposures can cause a build-up
of fluid in the lungs.
Chronic health effects: Have not been tested.
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SULFURIC ACID
Acute health effects: Extremely corrosive; can severely irritate and
burn skin and eyes. Inhalation can irritate lungs, causing coughing and/or
shortness of breath; higher-level exposures can cause a build-up of fluid in
the lungs.
Chronic health effects: Limited evidence that sulfuric acid causes
lung cancer in refinery workers. Repeated exposure can cause bronchitis, with
cough, phlegm, and shortness of breath; may cause emphysema; can cause chronic
runny nose, tearing of the eyes, nosebleeds, and stomach upset.
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T
TETRACHLOROETHYLENE
Acute health effects: Contact can cause skin irritation and burns.
Exposure can irritate eyes, nose, mouth, and throat. Inhalation can irritate
lungs, causing coughing and/or shortness of breath; higher-level exposures
can cause a build-up of fluid in the lungs. At high levels, exposure can cause
headache, dizziness, lightheadedness, nausea, vomiting, and unconsciousness.
Chronic health effects: May be a human carcinogen. May damage the
developing fetus. May damage the liver and kidneys and affect the nervous system.
Long-term exposure can cause drying and cracking of the skin.
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TOLUENE
Acute health effects: Contact can irritate skin and eyes. Inhalation
can irritate nose and throat, causing coughing and wheezing. Exposure can affect
the nervous system, causing trouble concentrating, headaches, slowed reflexes,
loss of appetite, and nausea. Higher levels can cause dizziness and lightheadedness,
which can lead to unconsciousness or death.
Chronic health effects: May damage a developing fetus. Prolonged contact
can cause drying and cracking of skin, as well as itching and a skin rash.
Repeated exposure may cause liver, kidney, and brain damage.
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1,1,1 TRICHLOROETHANE (a.k.a. METHYLCHLOROFORM)
Acute health effects: Can cause headaches, unsteadiness, fatigue, unconsciousness,
and death. Affects the nervous and cardiovascular systems. Exposure irritates
skin, eyes, nose, and throat.
Chronic health effects: Laboratory studies show repeated, high-level
exposure adversely affects liver, heart, and kidneys.
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TRICHLOROETHYLENE
Acute health effects: Contact can irritate and burn skin and eyes,
with possible eye damage. Exposure can cause lightheadedness, dizziness, unconsciousness,
visual disturbances, nausea, and vomiting. Very high levels can cause irregular
heartbeat, which can lead to death.
Chronic health effects: May cause lung and liver cancer. May cause
genetic changes. Repeated exposure can cause memory loss, headache, intolerance
to alcohol, depression, and weakness in the arms and legs. Repeated contact
can cause irritation, blistering, roughening, and cracking of exposed skin.
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TURPENTINE
Acute health effects: Contact can irritate and burn the eyes. Exposure
can irritate the nose and throat and can cause headaches, dizziness, nausea,
confusion, and rapid pulse. Inhalation can irritate the lungs, causing coughing
and/or shortness of breath; higher-level exposures can cause a build-up of
fluid in the lungs.
Chronic health effects: May damage the developing fetus. May damage
the kidneys, bladder, and nervous system. Can irritate the lungs; repeated
exposures may cause bronchitis, with cough, phlegm, and/or shortness of breath.
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X
XYLENE
Acute health effects: Can irritate skin and eyes. Inhalation can irritate
nose and throat, causing coughing and difficulty breathing. Can cause headache,
nausea, vomiting, tiredness, and stomach upset; high levels can cause dizziness,
lightheadedness, fatigue, confusion, unconsciousness, and death.
Chronic health effects: Can cause damage to the surface of the eye.
Can damage the liver and kidneys. May damage a developing fetus. Repeated exposure
can cause poor memory, difficulty in concentration, and other brain effects.
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